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Gluconeogenesis and ketogenesis in perfused livers from short-chain acyl-CoA dehydrogenase-deficient mice

✍ Scribed by H. Yamanaka; Y. Ueshima; T. Nakajima; N. Yoshida; F. Inoue; N. Kodo; A. Kinugasa; T. Sawada


Publisher
Springer
Year
1992
Tongue
English
Weight
157 KB
Volume
15
Category
Article
ISSN
0141-8955

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Disturbed hepatic carbohydrate managemen
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Medium-chain acyl-coenzyme A (CoA) dehydrogenase (MCAD) catalyzes crucial steps in mitochondrial fatty acid oxidation, a process that is of key relevance for maintenance of energy homeostasis, especially during high metabolic demand. To gain insight into the metabolic consequences of MCAD deficiency