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Glucokinase gene mutations are not a common cause of permanent neonatal diabetes in France


Publisher
Springer
Year
2002
Tongue
English
Weight
38 KB
Volume
45
Category
Article
ISSN
0012-186X

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Glucokinase is a key regulatory enzyme in the pancreatic beta-cell. It plays a crucial role in the regulation of insulin secretion and has been termed the glucose sensor in pancreatic beta-cells. Given its central role in the regulation of insulin release it is understandable that mutations in the g