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Glucocorticoids induce a 29 000 Mrprotein in DDT1MF-2 smooth muscle cells but not in the DDT1MF-2 GR glucocorticoid resistant variant

✍ Scribed by James S. Norris; Lawrence E. Cornett; Peter O. Kohler; Stewart L. MacLeod; Allan J. Syms; Roy G. Smith

Publisher
Springer
Year
1985
Tongue
English
Weight
494 KB
Volume
68
Category
Article
ISSN
0300-8177

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Glucocorticoid induction of β-adrenergic receptors in the DDT1MF-2 smooth muscle cell line involves synthesis of new receptor
✍ James S. Norris; Pamela Brown; Jeffrey Cohen; Lawrence E. Cornett; Peter O. Kohl 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 529 KB

We have shown that glucocorticoids induce the appearance of beta 2-adrenergic receptors in membranes of the ductus deferens smooth muscle cell line (DDT1 MF-2). A concomitant increase in isoproterenol stimulated adenylate cyclase activity in the absence of exogenously applied GTP was observed as was