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Glucocorticoids Increase the Accumulation of Reactive Oxygen Species and Enhance Adriamycin-Induced Toxicity in Neuronal Culture

✍ Scribed by Laura J. McIntosh; Robert M. Sapolsky


Book ID
115606397
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
93 KB
Volume
141
Category
Article
ISSN
0014-4886

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## Abstract The protective effects of creatine against glutamate cytotoxicity have been demonstrated in neuronal cells and animal models of neurodegenerative diseases. The mechanisms underlying creatine neuroprotection against glutamate‐induced cell death are understood poorly. For the first time,