Surface roughness has been shown to affect differentiation and local factor production of MG63 osteoblastlike cells. This study examined whether surface roughness alters cellular response to circulating hormones such as 1β£,25-(OH) 2 D 3 . Unalloyed titanium (Ti) disks were pretreated with HF/HNO 3 (
Glucocorticoids increase osteoblast-like bone cell response to 1,25(OH)2D3
β Scribed by Wong, Glenda L.; Lukert, Barbara P.; Adams, John S.
- Book ID
- 109718641
- Publisher
- Nature Publishing Group
- Year
- 1980
- Tongue
- English
- Weight
- 444 KB
- Volume
- 285
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/285254a0
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We investigated the existence of a capacitative Ca2+ entry (CCE) pathway in ROS 17/2.8 osteoblast-like cells and its responsiveness to 1,25-dihydroxy-vitamin D3 [1,25(OH)2D3]. Depletion of inner Ca2+ stores with thapsigargin or 1,25(OH)2D3 in the absence of extracellular Ca2+ transiently elevated cy
Surface roughness affects proliferation, differentiation (alkaline phosphatase and osteocalcin), local factor production [transforming growth factor (TGFβ€) and prostaglandin E 2 (PGE 2 )], and response to 1,25-(OH) 2 D 3 (1,25) of MG63 osteoblast-like cells. In this study, we examined whether the ef