Glucocorticoids increase CD4+CD25high cell percentage and Foxp3 expression in patients with multiple sclerosis
β Scribed by M. Braitch; S. Harikrishnan; R. A. Robins; C. Nichols; A. J. Fahey; L. Showe; C. S. Constantinescu
- Book ID
- 109338858
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 195 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0001-6314
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## Abstract Accumulating evidence indicates an immunosuppressive role for CD4^+^CD25^+^ regulatory T cells (Tregs) in autoimmune diseases. Although an impaired Treg function in patients with relapsingβremitting multiple sclerosis (RRβMS) has been reported recently, no information is available so fa
## Abstract Regulatory T cells (Treg cells) have been well documented to have a crucial physiological role in preventing the development of autoimmune diseases and keeping selfβtolerance. Foxp3, a recently identified member of the forkhead transcription factors, serves as a master regulator for the