𝔖 Bobbio Scriptorium
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Glucocorticoids exert opposing effects on macrophage function dependent on their concentration

✍ Scribed by Hee-Young Lim; Nora Müller; Marco J. Herold; Jens Van Den Brandt; Holger M. Reichardt

Book ID
108782107
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
620 KB
Volume
122
Category
Article
ISSN
0019-2805

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## Abstract In the present studies, we utilized prostate cancer cell culture models to elucidate the mechanisms of action of broccoli‐derived phytochemicals 3,3′‐diindolylmethane (DIM) and indole‐3‐carbinol (I3C). We found DIM and I3C at 1–5 µM inhibited androgen and estrogen‐mediated pathways and