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Glucocorticoid receptor isoforms in human hepatocarcinoma HepG2 and SaOS-2 osteosarcoma cells: Presence of glucocorticoid receptor alpha in mitochondria and of glucocorticoid receptor beta in nucleoli

✍ Scribed by Anna-Maria G. Psarra; Sylvia Solakidi; Ioannis P. Trougakos; Loukas H. Margaritis; Giannis Spyrou; Constantine E. Sekeris


Book ID
116307042
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
919 KB
Volume
37
Category
Article
ISSN
1357-2725

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Hepatocellular carcinoma is the leading cause of male cancer death in Taiwan. We have found that the level of glucocorticoid receptor in hepatocellular carcinoma is significantly higher than that in the peritumoral tissue. In this study, we used a rat liver glucocorticoid receptor complementary DNA