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Glucocorticoid receptor in cultured human skin fibroblasts

✍ Scribed by Peter F. Bruning; Walter J. Meyer III; Claude J. Migeon


Book ID
116001827
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
554 KB
Volume
10
Category
Article
ISSN
0022-4731

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The uptake of glucocorticoids by cultured human skin keratinocytes and fibroblasts was found to be a rapid, temperature-sensitive process. All glucocorticoids tested accumulated in the cells, and the ratio between the intracellular and extracellular concentrations (q/Co ratio) was higher than 1. For