Glucocorticoid mediated transcriptional repression of c-myc in apoptotic human leukemic CEM cells
β Scribed by Feng Zhou; Rheem D Medh; E.Brad Thompson
- Book ID
- 117668030
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 828 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0960-0760
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## Abstract Treatment of CEMβC7 cells with glucocorticoids produces a 2.5βfold increase in the activity of the enzyme glutamine synthetase (GS). This increase is specific for steroids with glucocorticoid activity and occurs over a range of steroid concentrations consistent with a receptorβmediated
## Abstract Glucose metabolism of human leukemic cell lines CEMβC7 and CEMβC1 was investigated in vivo by ^13^C NMR using ^13^Cβlabeled glucose. Exact knowledge of glucose concentration, cell count, and cell viability of the cell suspensions made it possible to analyze glucose metabolism in detail.