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Glucocerebrosidase L444P mutation confers genetic risk for Parkinson’s disease in central China

✍ Scribed by Youpei Wang, Ling Liu, Jing Xiong, Xiaowei Zhang, Zhenzhen Chen, Lan Yu, Chunnuan Chen, Jinsha Huang, Zhentao Zhang, Asrah A Mohmed, Zhicheng Lin, Nian Xiong, Tao Wang


Book ID
119909458
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
167 KB
Volume
8
Category
Article
ISSN
1744-9081

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Glucocerebrosidase Gene L444P mutation i
✍ Qi-Ying Sun; Ji-Feng Guo; Lei Wang; Ren-He Yu; Xing Zuo; Ling-Yan Yao; Qian Pan; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 457 KB

## Abstract An association between mutations in the __glucocerebrosidase__ (__GBA__) gene and Parkinson's disease (PD) has been reported in several populations. We searched for four common __GBA__ mutations (L444P, F213I, R353W, and N370S) in 402 Chinese PD patients and 413 age‐ and sex‐matched con