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Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic islets

✍ Scribed by W. E. Schmidt; E. G. Siegel; W. Creutzfeldt


Publisher
Springer
Year
1985
Tongue
English
Weight
433 KB
Volume
28
Category
Article
ISSN
0012-186X

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In this study, AR42J pancreatic acinar cells were used to investigate if glucagonlike peptide-1 (GLP-1) or glucagon might influence amylase release and acinar cell function. We first confirmed the presence of GLP-1 receptors on AR42J cells by reverse trasncriptase-polymerase chain reaction (RT-PCR),