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GLT-1 up-regulation enhances the effect of PCP on prepulse inhibition of the startle reflex in adult rats

โœ Scribed by Marcello Melone; Michele Bellesi; Alessandro Gubbini; Fiorenzo Conti

Book ID
119364154
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
110 KB
Volume
109
Category
Article
ISSN
0920-9964

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GLT-1 upregulation impairs prepulse inhibition of the startle reflex in adult rats
โœ Michele Bellesi; Marcello Melone; Alessandro Gubbini; Silvia Battistacci; Fioren ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 235 KB

## Abstract We tested the hypothesis that glutamate transporter GLTโ€1 (also known as EAAT2) plays a role in the regulation of prepulse inhibition (PPI) of the acoustic startle reflex, a simple form of information processing which is reduced in schizophrenia. To do this, we studied PPI in rats treat