Glottic cancer involving anterior commissure: Surgery vs radiotherapy

✍ Scribed by Dr. Lucio Rucci; Oreste Gallo; Omero Fini-Storchi

• Book ID: 102848052
• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 659 KB
• Volume: 13
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/hed.2880130505

✦ Synopsis

A retrospective review of 182 patients with glottic cancer involving the anterior commissure (AC) is presented. of these, 123 patients were first treated with conservative surgery and 59 underwent radiotherapy. Patients were staged according to the AJCC system and by the modality of neoplastic involvement of AC (pure AC cancer, glottic cancer involving AC up to the midline, and beyond the midline). Our results indicate a higher rate of local control and of specific-disease survival in the group of patients first treated with surgery than those treated with radiotherapy (86% vs 74% and 97.5% vs 84%, rppectively) @ c 0.05). For pure AC cancers, our results show better local control with primary radiotherapy than with conservation surgery (82% vs 76.5%), but surgical failures have been more successfully salvaged than have radiotherapy recurrences (ultimate local control, 97.5% vs 820% respectively). These data suggest that the treatment of choice for AC cancers is conservation surgery, particularly frontolateral laryngectomy. HEAD 8 NECK 1991;13:403410

T h e anterior commissure (AC) of the larynx constitutes a transitional zone between the supraglottic and glottic region and is frequently involved by tumor. The neoplastic involvement of the AC is rarely an isolated cancer growth in the From the llnd Otorhinolaryngologic Clinic,