Glomerular filtration: the charge debate charges ahead
β Scribed by Miner, Jeffrey H
- Book ID
- 124088811
- Publisher
- Nature Publishing Group
- Year
- 2008
- Tongue
- English
- Weight
- 473 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0085-2538
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π SIMILAR VOLUMES
Albuminuria is the first clinical event in the development of diabetic nephropathy. We assessed glomerular charge- and size selectivity in 51 patients with Type 1 (insulin-dependent) diabetes mellitus of juvenile onset and 11 healthy individuals. Patients were allocated to five groups. The urinary a
The selectivity index, i.e. clearance of non glycated albumin/clearance of glycated albumin was studied in fourteen patients with Type 1 (insulin-dependent) diabetes and normal urinary albumin excretion. The index was increased above one in all patients, and correlated significantly to HbA1c. It was