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Globus pallidus internus deep brain stimulation for dystonic conditions: A prospective audit

✍ Scribed by John Yianni; Peter Bain; Nir Giladi; Marieta Auca; Ralph Gregory; Carole Joint; Dipankar Nandi; John Stein; Richard Scott; Tipu Aziz

Book ID
102944271
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
775 KB
Volume
18
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

In the current era of functional surgery for movement disorders, deep brain stimulation (DBS) of the globus pallidus internus (GPi) is emerging as the favoured target in the treatment of patients with dystonia. The results of 25 consecutive patients with medically intractable dystonia (12 with generalised dystonia, 7 with spasmodic torticollis, and 6 with other types of dystonia) treated with GPi stimulation are reported. Although comparisons were limited by differences in their respective neurological rating scales, chronic DBS benefited all groups, resulting in clear and progressive improvements in their condition. This study clearly demonstrates that DBS of the GPi provides amelioration of intractable dystonia. Β© 2002 Movement Disorder Society

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## Abstract The clinical response of a 53‐year‐old woman with tardive dyskinesia treated with bilateral globus pallidus interna deep brain stimulation is described. At 18 months follow‐up, her Burke–Fahn–Marsden Dystonia Rating Scale score fell from 52 (preoperative) to 21 (60% improvement). Β© 2004