GLOBIN SYNTHESIS IN SEVERE AND INTERMEDIATE HOMOZYGOUS β THALASSEMIA IN ISRAEL
✍ Scribed by Gabriel Cividalli; Helen Kerem; Eliezer A. Rachmilewitz
- Book ID
- 118718585
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 344 KB
- Volume
- 344
- Category
- Article
- ISSN
- 0890-6564
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📜 SIMILAR VOLUMES
Homozygous beta-thalassemia intermediate (TI) differs from thalassemia major (TM) in being less severe clinically. Associated alpha-thalassemia could account for the TI phenotype by reducing the alpha/non-alpha chain imbalance. We have analyzed the alpha loci of 9 TI and 11 TM patients by restrictio
Alpha-globin genes were analyzed by the direct method of DNA mapping using alpha- and zeta-globin specific probes in a Thai family in which the proposita was an unusually mild beta zero-thalassemia homozygote. alpha zero-Thalassemia was found to be segregating in the family, inherited from the propo