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Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes

✍ Scribed by B. M. Herrera; H. E. Lockstone; J. M. Taylor; M. Ria; A. Barrett; S. Collins; P. Kaisaki; K. Argoud; C. Fernandez; M. E. Travers; J. P. Grew; J. C. Randall; A. L. Gloyn; D. Gauguier; M. I. McCarthy; C. M. Lindgren


Publisher
Springer
Year
2010
Tongue
English
Weight
314 KB
Volume
53
Category
Article
ISSN
0012-186X

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✍ B. L. Maloff; B. K. Boyd πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 644 KB

A B-cell-deficient model for Type 2 (non-insulindependent) diabetes mellitus has been investigated with regard to insulin action at the cellular level. Two-day-old male Sprague Dawley rats were injected with streptozotocin (90 mg/kg) or citrate buffer. At 6 weeks streptozotocin-treated animals were