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Global DNA methylation in old subjects is correlated with frailty

✍ Scribed by Dina Bellizzi; Patrizia D’Aquila; Alberto Montesanto; Andrea Corsonello; Vincenzo Mari; Bruno Mazzei; Fabrizia Lattanzio; Giuseppe Passarino


Book ID
106575573
Publisher
Springer Netherlands
Year
2011
Tongue
English
Weight
331 KB
Volume
34
Category
Article
ISSN
0161-9152

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## Abstract Epigenetic silencing of genes by aberrant DNA methylation is recognized as a crucial component of the mechanism underlying tumorigenesis. However, the relationship between DNA methylation and the past lifestyle in cancer patients remains largely unknown. We examined the methylation stat