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Global DNA methylation and tumor suppressor gene promoter methylation and gastric cancer risk in an Omani Arab population

✍ Scribed by Rusiecki, Jennifer A; Al-Nabhani, Maryam; Tarantini, Letizia; Chen, Ligong; Baccarelli, Andrea; Al-Moundhri, Mansour S


Book ID
120203242
Publisher
Future Medicine
Year
2011
Tongue
English
Weight
737 KB
Volume
3
Category
Article
ISSN
1750-1911

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## Abstract Retinoic acid receptor B2 (__RARB2__) is frequently inactivated in cancer. Methylation in the 5′‐untranslated region and first exon is known to play a role; however, few studies have analyzed the detailed methylation pattern of the promoter region. We show that hypo‐ and hypermethylated