The stability of the classical Levin-Stewart model that describes the competition between plasmid-bearing and plasmid-free populations in a chemostat is revisited using a combination of bifurcation theory and continuation techniques. Simple analytical conditions are derived that describe the conditi
β¦ LIBER β¦
Global analysis of a model of plasmid-bearing, plasmid-free competition in a chemostat
β Scribed by Sze-Bi Hsu; Paul Waltman; Gail S. K. Wolkowicz
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 629 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0303-6812
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β¦ Synopsis
A model of competition between plasmid-bearing and plasmid-free organisms in a chemostat was proposed in a paper of Stephanopoulis and Lapidus. The model was in the form of a system of nonlinear ordinary differential equations. Such models are relevant to commercial production by genetically altered organisms in continuous culture. The analysis there was local (using index arguments). This paper provides a mathematically rigorous analysis of the global asymptotic behavior of the governing equations in the case of uninhibited specific growth rate.
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