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Global analysis of a model of plasmid-bearing, plasmid-free competition in a chemostat

✍ Scribed by Sze-Bi Hsu; Paul Waltman; Gail S. K. Wolkowicz


Publisher
Springer
Year
1994
Tongue
English
Weight
629 KB
Volume
32
Category
Article
ISSN
0303-6812

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✦ Synopsis


A model of competition between plasmid-bearing and plasmid-free organisms in a chemostat was proposed in a paper of Stephanopoulis and Lapidus. The model was in the form of a system of nonlinear ordinary differential equations. Such models are relevant to commercial production by genetically altered organisms in continuous culture. The analysis there was local (using index arguments). This paper provides a mathematically rigorous analysis of the global asymptotic behavior of the governing equations in the case of uninhibited specific growth rate.


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Competition of plasmid-bearing and plasm
✍ K. Alhumaizi; A. Alwan; A. Ajbar πŸ“‚ Article πŸ“… 2006 πŸ› Elsevier Science 🌐 English βš– 882 KB

The stability of the classical Levin-Stewart model that describes the competition between plasmid-bearing and plasmid-free populations in a chemostat is revisited using a combination of bifurcation theory and continuation techniques. Simple analytical conditions are derived that describe the conditi