This paper investigates the global stability of virus dynamics model with Beddington-DeAngelis infection rate. By constructing Lyapunov functions, the global properties have been analysed. If the basic reproductive ratio of the virus is less than or equal to one, the uninfected steady state is globa
Global analysis for delay virus dynamics model with Beddington–DeAngelis functional response
✍ Scribed by Gang Huang; Wanbiao Ma; Yasuhiro Takeuchi
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 215 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0893-9659
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✦ Synopsis
A class of virus dynamics model with intracellular delay and nonlinear infection rate of Beddington-DeAngelis functional response is analysed in this paper. By constructing suitable Lyapunov functionals and using LaSalle-type theorem for delay differential equations, we show that the global stability of the infection-free equilibrium and the infected equilibrium depends on the basic reproductive ratio R 0 , that is, the former is globally stable if R 0 ≤ 1 and so is the latter if R 0 > 1. Our results extend the known results on delay virus dynamics considered in the other papers and suggest useful methods to control virus infection.
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