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Glioma cell activation by Alzheimer's peptide Aβ1–42,α1-antichymotrypsin, and their mixture

✍ Scribed by Y. X. Sun; H. T. Wright; S. Janciauskiene


Book ID
105748778
Publisher
Springer
Year
2002
Tongue
English
Weight
200 KB
Volume
59
Category
Article
ISSN
1420-682X

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α1-Antichymotrypsin/Alzheimer's peptide
✍ Yong-Xin Sun; H.T. Wright; S. Janciauskiene 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 948 KB

Amyloid-beta peptide (A␤) and the serpin proteinase inhibitor ␣1-antichymotrypsin (ACT) are components of the amyloid plaques associated with Alzheimer's disease (AD). A␤ exists in soluble monomeric and oligomeric forms and in an insoluble polymerised fibrillar form, but it is not clear which of the