Glial fibrillary acidic protein in mutant mice with deficiency of myelination: Quaking and jimpy
โ Scribed by A. Bignami; D. Dahl
- Book ID
- 104905480
- Publisher
- Springer-Verlag
- Year
- 1974
- Tongue
- English
- Weight
- 550 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0001-6322
No coin nor oath required. For personal study only.
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## Abstract Myelin basic protein (MBP) was quantified using a RIA technique in the spinal cord, cerebellum, diencephalon plus brainstem region and cerebral hemispheres of two dysmyelinating murine mutants, quaking (qk) and jimpy (jp) mice. Comparison was made with normal control values. The whole l
A method to purify glial fibrillary acidic protein (GFAP) from mouse spinal cord is described, which permits the measurement of GFAP in the sciatic nerve of the twitcher mutant and control mouse. Cytoskeletal proteins from sciatic nerves and purified GFAP standards were electrophoresed on gel, trans