Glial cell line-derived neurotrophic factor (GDNF) was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is a more potent survival factor for dopaminergic neurons and the noradrenerg
Glial cell line-derived neurotrophic factor and synaptophysin expression in pelviureteral junction obstruction
✍ Scribed by Savaş Demirbilek; Mehmet Naci Edali; Kubilay Gürünlüoğlu; Emine Türkmen; Erkan Taş; Abdurrahman Karaman; Melih Akın; Rauf Tuğrul Aksoy; Osman Celbis; ̇Ibrahim Üzün
- Book ID
- 116945464
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 781 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0090-4295
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Glial cell line-derived neurotrophic factor (GDNF) has been shown to exert neurotrophic effects on motor neurons as well as mesencephalic dopaminergic neurons. Because GDNF promotes survival of motor neurons in vivo and in vitro and rescues motor neurons from naturally occurring cell death, the pote
Glial cell line-derived neurotrophic factor (GDNF) has been shown to be a preferentially selective neurotrophic factor for dopamine (DA) neurons. In the present study, we have examined the distribution of GDNF mRNA expression in several major DA-containing cell body and terminal areas and the regula