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Glial cell-derived neurotrophic factor gene delivery enhances survival of human corneal epithelium in culture and the overexpression of GDNF in bioengineered constructs

✍ Scribed by Hong Qi; H. David Shine; De-Quan Li; Cintia S. de Paiva; William J. Farley; Dan B. Jones; Stephen C. Pflugfelder


Book ID
116456814
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
443 KB
Volume
87
Category
Article
ISSN
0014-4835

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Glial cell line-derived neurotrophic fac
✍ Yan, Qiao ;Wang, Jue ;Matheson, Christine R. ;Urich, Janal L. πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 842 KB

Adult rat retinal ganglion cells (RGC) undergo degeneration after optic nerve transection. Studies have shown that exogenously applied neurotrophic factors such as brain-derived neurotrophic factor (BDNF) can attenuate axotomy-induced as well as developmental RGC death. Here, we examined whether gli