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Glia activation induced by peripheral administration of aluminum oxide nanoparticles in rat brains

✍ Scribed by Xiao-bo Li; Hao Zheng; Zhi-ren Zhang; Miao Li; Zhi-yong Huang; Hermann J. Schluesener; Yuan-yuan Li; Shun-qing Xu

Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 598 KB
Volume: 5
Category: Article
ISSN: 1549-9634
DOI: 10.1016/j.nano.2009.01.013

No coin nor oath required. For personal study only.

✦ Synopsis

From the clinical editor:

Sprague-dawley rats were intraperitoneally injected with nanosized aluminum oxide, (nsao); non-nanoscaled aluminum oxide, or vehicle (saline). the numbers of ed1+, gfap+, and nestin+ cells in cortex and hippocampus were significantly higher in nsao-treated rats than nnsao- or vehicle-treated rats; thus, nsao has potential effects on the innate immune system of rat brain.

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