GLC determination of ethylene chlorohydrin following co-sweep extraction

✍ Scribed by Joseph Weinberger

• Publisher: John Wiley and Sons
• Year: 1971
• Tongue: English
• Weight: 337 KB
• Volume: 60
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600600406

✦ Synopsis

A Co-Sweep extraction method was developed for removing and concentrating trace amounts of ethylene chlorohydrin from a variety of materials which were sterilized with ethylene oxide. Samples placed inside glass tubes were extracted in an apparatus with the aid of heat, solvents, and a continuous flow of carrier gas. The volatilized solvents were condensed in a cooling coil and swept into a collection tube. The entire extraction procedure was accomplished within 35 min. GLC was used to analyze the extract for ethylene chlorohydrin in the nanogram range. An ethylene chlorohydrin recovery study was performed in the microgram per gram range on different types of samples. The results indicate that the Co-Sweep technique is reliable, simple to ope1 ate, and potentially applicable to a wide variety of materials.