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GLC analysis of thioridazine, mesoridazine, and their metabolites

✍ Scribed by Eugene C. Dinovo; Louis A. Gottschalk; Bina Rani Nandi; Peter G. Geddes

Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
322 KB
Volume
65
Category
Article
ISSN
0022-3549

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Five acute schizophrenic patients were given a standard thioridazine dose (4 mg/kg/day po). Their plasma concentrations of thioridazine and its metabolites were determined by GLC, and their ECG's were recorded routinely. In four of the five patients, abnormal ECG's (malformation of the T-wave or len

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