Glassy Carbon Paste Electrodes for the Determination of Fructosyl Valine

✍ Scribed by Hui-Ching Chien; Tse-Chuan Chou

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 226 KB
• Volume: 22
• Category: Article
• ISSN: 1040-0397
• DOI: 10.1002/elan.200900384

✦ Synopsis

Abstract

Nearly 200 million people worldwide have type‐2 diabetes. Glucose sensors are routinely used for diagnosis; however, the relative amount of glycosylated hemoglobin (HbA1c) may be a better marker. A working electrode made from bare glassy carbon paste was used for sensing fructosyl valine (Fru‐Val), a component of HbA1c. Amperometric measurements revealed a linear relationship between Fru‐Val concentration and the sensing current. The square correlation coefficient and the sensitivity were 0.999 and 5.26 μA mM^−1^, respectively. The minimum detection limit was less than 0.05 mM.