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GIRK2 deficient mice: Evidence for hyperactivity and reduced anxiety

✍ Scribed by Yuri A Blednov; M Stoffel; S.R Chang; R Adron Harris

Book ID
117197561
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
253 KB
Volume
74
Category
Article
ISSN
0031-9384

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## Abstract Canonical Wnt signaling involves complex intracellular events culminating in the stabilization of β‐catenin, which enters the nucleus and binds to LEF/TCF transcription factors to stimulate gene expression. __Pygopus__ was identified as a genetic modifier of Wg (Wnt homolog) signaling i