Ginsenoside Rb1 Inhibits Cell Activation and Liver Fibrosis in Rat Hepatic Stellate Cells
β Scribed by Lo, Yu-Ting; Tsai, Ya-Hui; Wu, Shu-Ju; Chen, Jiun-Rong; Chao, Jane C.-J.
- Book ID
- 118252417
- Publisher
- Mary Ann Liebert
- Year
- 2011
- Tongue
- English
- Weight
- 500 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1096-620X
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## Abstract ## Background/aims Transforming growth factor Ξ² (TGFΞ²1) is considered the key mediator in the process of liver fibrosis. The purpose of this investigation was to evaluate the activity of ribozymes against TGFΞ²1 in a cellβfree system and activated hepatic stellate cells (HSCs), and anti
procollagen type I, fibronectin, and laminin in the DMN Interferon gamma (IFN-g) inhibits in vitro the activa-/ IFN-g group. Thus, this study indicates that IFN-g retion of hepatic stellate cells (HSC), the primary extracelduces extracellular matrix deposition in vivo by inhibilular matrix-producing