Evidence for a gene cluster involving tr
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Thomas M. Hohn; Susan P. McCormick; Anne E. Desjardins
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Article
📅
1993
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Springer-Verlag
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English
⚖ 470 KB
Two overlapping cosmid clones (Cos1-1 and Cos9-1) carrying the Tox5 gene were isolated from a library of F. sporotrichioides strain NRRL 3299 genomic DNA. These cosmids were used to transform three T-2 toxin-deficient mutants that are blocked at different steps in the trichothecene pathway. Both cos