Giant cell tumor of the larynx: Case report and review of the literature

✍ Scribed by Jochen A. Werner; Dieter Harms; Arwed Beigel

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 332 KB
• Volume: 19
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/(sici)1097-0347(199703)19:2<153::aid-hed12>3.0.co;2-e

✦ Synopsis

Background: Primary manifestation of a giant cell chondrosarcomas. The primary manifestation of tumor (GCT) in the larynx is exceedingly rare. Until now, only 17 a giant cell tumor (GCT) in the larynx is exceedcases have been reported in the literature. Characterization of a GCT can be difficult partly because of similarities with the giant ingly rare. Until now, only 17 cases have been cell subtype of malignant fibrous histiocytoma (MFH). described in the international literature. 1-17 (One Methods: The case of a 35-year-old man with a laryngeal of these cases came from the Department of Oto-GCT is presented. The patient underwent laryngectomy and has rhinolaryngology, Head and Neck Surgery, at the been free of recurrence since then (90 months). The literature is University of Kiel. 3 ) The differential diagnosis reviewed, and previously reported cases are presented in a table and compared with the presented case. The difficulties in the can be difficult especially because the important differential diagnosis are discussed. differentiation from the giant cell subtype of the Conclusions: When a laryngeal GCT is diagnosed, further malignant fibrous histiocytoma is often problemdifferential diagnostic considerations should follow. One of these atic. Therapeutic options are surgery, radiotherconsiderations is the MFH, which displays considerably more apy, or a combination of both. The purpose of this cellular atypia than GCT. Because most cases of giant cell MFH are high-grade sarcomas, the distinction between GCT and MFH article is to present a new case of this rare maligis necessary.