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Gewinnung und Charakterisierung von Mutanten des Pilzes Penicillium cyclopium mit verändertem Entwicklungsprogramm

✍ Scribed by I. Schmidt; L. Nover; G. Ininger; Prof. Dr. M. Luckner


Book ID
102386754
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
456 KB
Volume
18
Category
Article
ISSN
0233-111X

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✦ Synopsis


Abstract

After treatment with NNMG, NaNO~2~ or UV‐light of conidiospores of Penicillium cyclopium strain SM 72 variant strains (mutants) with altered developmental programme were selected. Additionally from a methionine‐auxotrophic mutant of P. cyclopium prototrophic revertants were prepared. Investigation of the alkaloid metabolism and other idiophase processes has shown that these mutant strains can be divided into two groups (cf. table 1):

Mutants with a depression of all idiophase features. The defects of these strains presumably affect central regulatory processes which, as in strain rev‐met 83a, can be reversed spontaneously by an one‐step mechanism and

Mutants defective in certain parts of the idiophase programme only, demonstrating that there is a certain autonomy in regulation of the individual parts of the programme.