Getting rid of the PMS2 pseudogenes: mission impossible?
✍ Scribed by Renée C. Niessen; Jan H. Kleibeuker; Paul O.J. Jager; Rolf H. Sijmons; Robert M.W. Hofstra
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 91 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1059-7794
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possibility because employees will often credit their supervisors' ideas on unionization more than those of top management. Utilizing supervisors and providing them with the information to give to employees will put the union on the defensive early in the campaign.
Lynch syndrome is characterized by mutations in the mismatch repair genes MLH1, MSH2, MSH6, and PMS2. In PMS2, detection of mutations is confounded by numerous pseudogenes. Detection of 3 0 deletions is particularly complicated by the pseudogene PMS2CL, which has strong similarity to PMS2 exons 9 an