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Gestational diabetes and the adenosine/l-Arginine/nitric oxide (ALANO) pathway in human umbilical vein endothelium

✍ Scribed by R. San Martín; L. Sobrevia


Book ID
113853970
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
287 KB
Volume
27
Category
Article
ISSN
0143-4004

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Nitric oxide reduces adenosine transport
✍ Marcelo Farías; Rody San Martín; Carlos Puebla; Jeremy D. Pearson; Javier F. Cas 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 356 KB

## Abstract Human umbilical vein endothelial cells (HUVEC) from gestational diabetes exhibit reduced adenosine uptake and increased nitric oxide (NO) synthesis. Adenosine transport via human equilibrative nucleoside transporters 1 (hENT1) is reduced by NO by unknown mechanisms in HUVEC. We examined