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Germline transcripts of the immunoglobulin heavy-chain and T cell receptor genes in a murine hematopoietic stem cell line LyD9 and its derivative cell lines

✍ Scribed by Kei Tashiro; Tatsuo Kinashi; Steven J. Anderson; Kwang Ho Lee; Kaoru Tohyama; Masako Ogawa; Masazumi Takahashi; Masashi Kawaichi; Tasuku Honjo

Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 696 KB
Volume: 28
Category: Article
ISSN: 0165-2478
DOI: 10.1016/0165-2478(91)90113-o

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Expression of gene transcripts for immunoglobulins and a T-cell receptor was investigated in non-hematopoietic tumor cell lines using the highly sensitive RT-nested PCR method. These proteins are reported to be produced and secreted or expressed in malignancies originating from hematopoietic organs