Germline TP53 mutations and Li-Fraumeni
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J.M. Varley
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Article
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2003
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John Wiley and Sons
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English
β 126 KB
There are now reports of nearly 250 independent germline TP53 (p53) mutations in over 100 publications. Such mutations are typically associated with Li-Fraumeni or Li-Fraumeni-like syndrome, although many have been identified in cohorts of patients with tumors considered to be typical of LFS. In gen