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Germline TP53 Mutations and Li-Fraumeni Syndrome

✍ Scribed by J.M. Varley


Book ID
102259582
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
43 KB
Volume
21
Category
Article
ISSN
1059-7794

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Germline TP53 mutations and Li-Fraumeni
✍ J.M. Varley πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 126 KB

There are now reports of nearly 250 independent germline TP53 (p53) mutations in over 100 publications. Such mutations are typically associated with Li-Fraumeni or Li-Fraumeni-like syndrome, although many have been identified in cohorts of patients with tumors considered to be typical of LFS. In gen