Germline stem cells in the Drosophila ovary descend from pole cells in the anterior region of the embryonic gonad
β Scribed by Asaoka, M.
- Book ID
- 120975697
- Publisher
- The Company of Biologists Ltd
- Year
- 2004
- Tongue
- English
- Weight
- 747 KB
- Volume
- 131
- Category
- Article
- ISSN
- 0950-1991
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π SIMILAR VOLUMES
How stem cells are recruited to and maintained in their niches is crucial to understanding their regulation and use in regenerative medicine. Here, we demonstrate that DE-cadherinβmediated cell adhesion is required for anchoring germline stem cells (GSCs) in their niches in the __Drosophila__ ovary.
In the adult Drosophila ovary the continuous production of eggs depends upon a small group of stem cells located at the anterior tip of the germarium. These stem cells divide asymmetrically to self renew and to generate a cystoblast, which in females is committed to the oocyte differentiation pathwa