𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Germline mutations of BRCA1-associated RING domain (BARD1) gene in breast and/or ovarian families negative for BRCA1 and 2 alterations

✍ Scribed by C Ghimenti, E Sensi, D Iandolo, G Cipollini, S Ricci, PF Conte…

Book ID
120700562
Publisher
BioMed Central
Year
2000
Tongue
English
Weight
298 KB
Volume
2
Category
Article
ISSN
1465-5411

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Germline mutations of the BRCA1-associat
Germline mutations of the BRCA1-associated ring domain (BARD1) gene in breast and breast/ovarian families negative for BRCA1 and BRCA2 alterations
✍ Chiara Ghimenti; Elisa Sensi; Silvano Presciuttini; Isa Maura Brunetti; PierFran 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB 👁 3 views

## Abstract BARD1 (BRCA1‐associated RING domain) was identified by yeast two‐hybrid screening as a protein interacting with BRCA1. Somatic and germline mutations of __BARD1__ have been detected in sporadic breast, ovarian, and endometrial cancers. The present study represents the first description

Germline mutations of BRCA1 and BRCA2 in
Germline mutations of BRCA1 and BRCA2 in Korean breast and/or ovarian cancer families
✍ Hio Chung Kang; Il-Jin Kim; Jae-Hyun Park; Hyuk-Jun Kwon; Yong-Jin Won; Seung Ch 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 140 KB 👁 2 views

Germline mutations in the BRCA1 and BRCA2 genes are responsible for the predisposition and development of familial breast and/or ovarian cancer. Most mutations of BRCA1 and BRCA2 associated with breast and/or ovarian cancer result in truncated proteins. To investigate the presence of BRCA1 and BRCA2

Novel germline mutations in the BRCA1 an
Novel germline mutations in the BRCA1 and BRCA2 genes in Indian breast and breast-ovarian cancer families
✍ Mani T. Valarmathi; Meenakshi Sawhney; Suryanarayana S. V. Deo; Nootan K. Shukla 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB 👁 2 views

The two major hereditary breast/ovarian cancer predisposition tumor suppressor genes, BRCA1 and BRCA2 that perform apparently generic cellular functions nonetheless cause tissue-specific syndromes in the human population when they are altered, or mutated in the germline. However, little is known abo