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Germline mutations in the CDKN1B gene encoding p27Kip1 are a rare cause of multiple endocrine neoplasia type 1

โœ Scribed by Martina Owens; Karen Stals; Sian Ellard; Bijay Vaidya


Book ID
108704237
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
82 KB
Volume
70
Category
Article
ISSN
0300-0664

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Germline mutations in the multiple endoc
โœ Matthew G. Mutch; William G. Dilley; Francisco Sanjurjo; Mary K. DeBenedetti; Ge ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 463 KB ๐Ÿ‘ 1 views

Multiple endocrine neoplasia type 1 (MEN 1) is a familial cancer syndrome characterized by parathyroid hyperplasia, pituitary adenomas, and neuroendocrine tumors of the pancreas and duodenum. In 1997, the MEN1 tumor suppressor gene was identified, and numerous germline mutations have been reported t