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Germinal center B cells in Peyer's patches of aged mice exhibit a normal activation phenotype and highly mutated IgM genes

✍ Scribed by Brian J Rogerson; David P Harris; Susan L Swain; D.Ollie Burgess

Book ID
114096276
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
811 KB
Volume
124
Category
Article
ISSN
0047-6374

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## Age-related decrease in the proportion of germinal center B cells from mouse Peyer's MRC, Laboratory of Molecular Biology, Cambridge patches is accompanied by an accumulation of somatic mutations in their immunoglobulin genes\* Somatic hypermutation of immunoglobulin genes and the generation of