Germ-line transcription of the T cell receptor δ gene in mouse hematopoietic cell lines
✍ Scribed by Michio Shimamura; Sachiko Ohta
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 882 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0014-2980
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Expression of gene transcripts for immunoglobulins and a T-cell receptor was investigated in non-hematopoietic tumor cell lines using the highly sensitive RT-nested PCR method. These proteins are reported to be produced and secreted or expressed in malignancies originating from hematopoietic organs
## Paris Malade% TheT cell receptor (TCR)-a and -6 loci are contained on the same chromosomal region, and yet are developmentally and genetically independent. The first element of the J a cluster (YJa) is the site of an active rearrangement in the human thymus (6Rec-YJa rearrangement) and is local