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Germ-cell mutagenicity of etoposide: induction of meiotic micronuclei in cultured rat seminiferous tubules

✍ Scribed by Tiina Sjöblam; Martti Parvinen; Jaana Lähdetie


Book ID
113255878
Publisher
Elsevier Science
Year
1994
Weight
359 KB
Volume
323
Category
Article
ISSN
0165-7992

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✍ Jaana Lähdetie; Kimmo Peltonen; Tiina Sjöblom 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB 👁 2 views

Three metabolites of the industrial chemical 1,3-butadiene (BD), namely butadiene monoepoxide (BMO, 3,4-epoxy-1-butene), diepoxide (DEB, 1,2;3,4-diepoxybutane), and diolepoxide (DE, 3,4- epoxybutane-1,2-diol) were studied for germ cell mutagenicity using the rat spermatid micronucleus (MN) test. All