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Geranylgeranyl-pyrophosphate (GGPP) synthase is down-regulated during differentiation of osteoblastic cell line MC3T3-E1

โœ Scribed by Tomohiko Yoshida; Mie Asanuma; Laura Grossmann; Masami Fuse; Takahisa Shibata; Taeko Yonekawa; Tomoaki Tanaka; Koichi Ueno; Tatsuji Yasuda; Yasushi Saito; Ichiro Tatsuno


Book ID
116466930
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
180 KB
Volume
580
Category
Article
ISSN
0014-5793

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## Abstract The orphan nuclear receptor Nurr1 is primarily expressed in the central nervous system. It has been shown that Nurr1 is necessary for terminal differentiation of dopaminergic (DA) neurons in ventral midbrain. The receptor, however, is also expressed in other organs including bone, even