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Genotyping of CYP2D6 gene in finnish lung cancer patients by PCR

✍ Scribed by A. Hirvonen; K. Husgafvel-Pursiainen; S. Anttila; A. Karjalainen; H. Vainio

Book ID
113252573
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
87 KB
Volume
271
Category
Article
ISSN
0165-1161

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The genetic polymorphism of the cytochrome P450 monooxygenase, CYP2D6, comprises at least 43 alleles giving rise to distinct drug metabolism phenotypes termed ultrarapid, extensive, intermediate, and poor metabolizers. As a consequence, drug side effects or lack of drug effect may occur if standard