Genotype–phenotype correlations in the genomic age: Concordance in monozygous twin pairs

Genomic changes defining the genesis, pr

Genomic changes defining the genesis, progression, and malignancy potential in solid human tumors: A phenotype/genotype correlation

✍ Thomas Ried; Kerstin Heselmeyer-Haddad; Harald Blegen; Evelin Schröck; Gert Auer 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 495 KB

The transition of normal epithelium to invasive carcinoma occurs sequentially. In colorectal and cervical carcinogenesis, this transition is reflected by histomorphologically defined grades of increasing dysplasia that untreated may progress to invasive disease. In an attempt to understand the role