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Genotype-phenotype studies in CDKN2A (p16INK4a/p14ARF) mutation positive and negative Australian high risk melanoma families

✍ Scribed by Angelo V. Sklavos; Richard F. Kefford; Dr Elizabeth. Gow; Dr Graham J. Mann


Book ID
116578487
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
57 KB
Volume
50
Category
Article
ISSN
1097-6787

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Mutation analysis of two genes involved in melanoma susceptibility (CDKN2A/p16 INK4a and CDK4) was undertaken in 131 probands with a family history of melanoma. Screening of all three exons of CDKN2A and exon 2 of CDK4 by single-strand conformation polymorphism (SSCP) analysis and/or direct sequenci