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Genotype of the CYBA promoter −930A/G, polymorphism C677T of the MTHFR and APOE genotype in patients with hypertensive disorders of pregnancy: An observational study

✍ Scribed by Pablo Stiefel; María Luisa Miranda; Lola M. Bellido; Jerónimo Luna; Luis Jiménez; Encarnación Pamies; Pablo García de Frutos; José Villar

Book ID
116739059
Publisher
Elsevier Science
Year
2009
Tongue
Spanish
Weight
140 KB
Volume
133
Category
Article
ISSN
0025-7753

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Linkage disequilibrium of MTHFR genotype
Linkage disequilibrium of MTHFR genotypes 677C/T-1298A/C in the German population and association studies in probands with neural tube defects(NTD)
✍ Stegmann, Karolin; Ziegler, Andreas; Ngo, Ernestine T. K. M.; Kohlschmidt, Nicol 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 32 KB 👁 1 views

A number of studies have demonstrated that the common polymorphism 677C→T in the gene encoding 5, 10-methylenetetrahydrofolate reductase (MTHFR) leads to a thermolabile variant with decreased enzyme activity and to mildly elevated plasma homocysteine. 677TT homozygosity was shown to be more frequent